The setting is important to the story because how is it supposed to take place. Like if it was underwater it won't make since why do they need weapons. They also will die from not breathing and hunger. Also if they had it in the desert were would they hide and they will die from the animals. So it is important for the place because it will be hard to hide.
It would be way different if it was somewhere else. Like if it was in Chicago it would look way different. Like district 12 would be like Cicero. But the whole thing would change. It would change by the main character being a city person. It would be weird.